通过皮肤进行高剂量间歇性支架疗法,用于肺和肝脏的非切除性,耐化疗的恶性病变
Nandlal Yadawa1, Uday P Shahi1, Abhijit Mandal1
1Department of Radiation Oncology, IMS BHU Varanasi, Uttar Pradesh, India.
Journal of cancer research and therapeutics
|February 22, 2024
概括
高剂量速率间歇性支臂疗法 (HDR ISBT) 为晚期肝癌和肺癌提供了最少侵入性的治疗方法. 这种技术显示出显著的瘤缩和最小的并发症在非切除,化疗耐药的病例.
科学领域:
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
- 最少侵入性手术的方法
背景情况:
- 晚期肝癌和肺癌往往表现为不可切除和耐化疗.
- 对于患有晚期,不可手术的恶性瘤的患者,存在有限的治疗选择.
研究的目的:
- 评估间歇性支架疗法对恶性肝脏和肺病变的可行性和有效性.
- 评估高剂量间歇性支架疗法 (HDR ISBT) 的治疗结果和并发症率.
主要方法:
- 通过皮肤的HDR ISBT应用于7名晚期癌症患者的9个病变.
- CT或USG指导用于注射针,剂量从15 Gy到20 Gy不等.
- 损伤大小决定了插入针的数量;治疗后对患者进行了监测.
主要成果:
- 病变的中位数大小为6.5厘米.
- 在6个月后,在肝病变中观察到超过75%的瘤体积缩小.
- 在肺病变中,超过50%的瘤缩小,没有报告显著的并发症.
结论:
- 穿皮CT导向的HDR ISBT是一种可行且安全的治疗方法,用于无法手术的,耐化疗的晚期癌症.
- 该程序显示了最小的并发症和令人鼓舞的治疗结果.
- 高清激光ISBT代表了一个有前途的微创性治疗选择,用于晚期恶性瘤.
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