口腔状细胞癌的侵入性前线的恶性瘤分级的预后影响
1Department of Oral and Maxillofacial Pathology, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.
Journal of cancer research and therapeutics
|February 22, 2024
概括
布莱恩恶性瘤分级系统显示,印度患者的口腔状细胞癌 (OSCC) 存活率具有显著的预后值. 这个系统有效地预测了整体生存率,超过了世卫组织的分级系统.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 手术瘤学手术瘤学
背景情况:
- 在西方研究中建立的布莱恩恶性瘤分级系统,因其在口腔状细胞癌 (OSCC) 的预后意义而得到认可.
- 与世界卫生组织 (WHO) 评分系统进行比较分析对于不同人群至关重要.
研究的目的:
- 评估修改后的布莱恩恶性瘤分级系统在印度人口中的预后意义.
- 为了比较布莱恩系统与世卫组织对印度OSCC的分级系统的有效性.
主要方法:
- 评估50名主要OSCC患者的大型手术切除样本记录.
- 用WHO分级系统和布莱恩恶性瘤分级系统对深入入侵前线进行血素和欧染色幻灯片的分析.
主要成果:
- 侵入性前线的组织病理学分级显示出显著的预后价值和与整体生存率的相关性.
- 卡普兰-梅尔生存分析表明,在Bryne分数≤12的情况下,五年生存率为60.6%,而在分数>12.2的情况下为17.6%.
- 世卫组织I级和II级的生存率为48.9%,而III级没有幸存者.
结论:
- 侵入性前部组织病理学是OSCC临床行为的关键预后指标.
- 布莱恩分级系统可以可靠地预测OSCC患者的整体存活率,特别是在印度人口统计学中.
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