双价COVID-19疫苗的相对有效性:一个系统的审查和元分析
Meng-Qun Cheng1, Rong Li2, Zhi-Ying Weng3
1Department of Reproductive Medicine, The Puer People's Hospital, Pu'er, China.
Frontiers in medicine
|February 22, 2024
概括
针对COVID-19的双价疫苗 (BVs) 在预防感染,住院和死亡方面显示出比单价疫苗 (MVs) 更高的有效性. 对于50岁以上的个人以及在Omicron XBB变种流通期间,BV提供了卓越的保护.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- COVID-19双价疫苗 (BVs) 迅速开发,针对原始和变种菌株.
- 与单价疫苗 (MVs) 相比,VVs的比较有效性在很大程度上仍未得到量化.
结论:
- 与单价疫苗 (MVs) 相比,双价疫苗 (BVs) 对与COVID-19相关的感染,住院和死亡提供更好的保护.
- 增强的BV疗效在老年人中尤其显著,并且在大量流通变种的时期尤其显著,例如Omicron XBB.
- 这些发现支持BVs在预防和控制新型冠状病毒变异的更广泛应用.
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