维生素D补充剂可以预防良性发性位置性的复发
Tae Hoon Kong1,2, Su Young Jung3, Young Joon Seo1,2
1Department of Otorhinolaryngology - Head and Neck Surgery Yonsei University Wonju College of Medicine Wonju-si Gangwon-do Korea.
Laryngoscope investigative otolaryngology
|February 22, 2024
概括
维生素D补充剂可以降低患有维生素D水平较低的患者患有良性发性位置性 (BPPV) 的复发率. 这项研究发现,与安慰剂相比,接受维生素D的患者BPPV复发率较低.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 良性发性位置性 (BPPV) 是导致头的常见原因.
- 血清维生素D水平低于最佳水平在BPPV患者中很普遍,可能与复发有关.
研究的目的:
- 调查维生素D补充剂在预防BPPV复发中的有效性.
- 评估血清维生素D水平与BPPV复发率之间的相关性.
主要方法:
- 一项前性,双盲,安慰剂对照试验,涉及38名BPPV患者,血清维生素D<20 ng/mL.
- 患者每周接受7000 IU维生素D或安慰剂,在canalith重新定位后一年.
- 复发率和血清维生素D水平在6个月和12个月后进行了监测.
主要成果:
- 维生素D组的血清维生素D水平在6个月和1年后显著上升 (p < .001).
- 维生素D组的BPPV复发在6个月 (p = .008) 和1年 (p = .003) 后显著降低.
结论:
- 补充维生素D似乎有利于降低BPPV复发在患者的维生素D水平低于最佳水平.
- 进一步的研究可能会探索维生素D在治疗复发性BPPV中的作用,可能没有.
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