缺少牙数量与高脂血症之间的关联:TCLSIH队列研究
Feng Qiao1,2, Hong Guo1,2, Jing Zhang1,2
1School of Dentistry, Stomatological Hospital, Tianjin Medical University, Tianjin, People's Republic of China.
Journal of inflammation research
|February 22, 2024
概括
缺失牙的数量与中国妇女患高脂血症的风险更高有关,但男性并非如此. 这种关联可能受到全身慢性炎症的影响.
科学领域:
- 口腔健康 口腔健康
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 超脂血症是一个重大的公共卫生挑战.
- 牙健康,特别是牙脱落,因其系统性影响而越来越受认可.
- 了解口腔健康和代谢性疾病之间的联系对于预防策略至关重要.
研究的目的:
- 调查缺失牙数量与高脂血症发生率之间的关联.
- 为了在一个大型的中国成年人群中分析这种关系.
- 为了确定这种关联中潜在的性别特异性差异.
主要方法:
- 研究了一组由13932名中国成年人组成的队列.
- 牙损失是自我报告和分类的 (0,1-2,≥3颗缺失牙).
- 使用定义的脂质水平和医生诊断来确定超脂血症发病率,通过考克斯回归分析.
主要成果:
- 在42,048人年中,发生了6756例高脂血症病例.
- 在女性中,牙损失的增加与高脂血症风险的显著增加相关 (趋势P<0.01).
- 在男性牙脱落和高脂血症发病率之间没有发现显著的关联 (P趋势=0.30).
结论:
- 失去牙与中国妇女患高脂血症的风险增加有关.
- 在中国男性中没有观察到这种关联.
- 系统性慢性炎症是这种观察到的联系的潜在调解因素.
相关概念视频
Blood Studies for Cardiovascular System III: Serum Lipid Profile
163
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
163
Lipids: Dietary Sources and Requirements
739
Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ...
739
Cholesterol: Significance and Regulation
544
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
544
Overview of Lipid Metabolism
1.6K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.6K
Teeth
417
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
417
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
661
Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
661


