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Updated: Jul 2, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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在肝细胞癌中,PPM1G通过调节突变GOF p53蛋白表达来促进细胞增殖

Wen Hu1, Shao-Lin Ma2, Liang Qiong1

  • 1Department of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510630, China.

iScience
|February 22, 2024
PubMed
概括

蛋白酸酶Mg2+/Mn2+依赖性1G (PPM1G) 在肝细胞癌 (HCC) 中过度表达,与患者生存率差相关. PPM1G通过与突变p53.3相互作用,促进HCC细胞增殖和瘤生长.

关键词:
生物化学 生物化学遗传学 是一个遗传学.分子遗传学 分子遗传学

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