后循环缺血性中风的发生率,临床特征和结果:来自大型多民族中风数据库的见解
Yahia Z Imam1,2,3, Prem Chandra4, Rajvir Singh5
1Neuroscience Institute, Hamad Medical Corporation, Doha, Qatar.
Frontiers in neurology
|February 22, 2024
概括
后循环缺血性中风 (PCS) 发病率正在上升,特别是在中东和北非 (MENA) 地区的男性中. 这项研究强调了中风位置和中风结果在MENA和非MENA人口之间的显著差异.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 公共卫生 公共卫生
背景情况:
- 后循环缺血性中风 (PCS) 占所有中风的25%.
- PCS呈现出不同的症状,往往导致误诊,发病率和死亡率.
- 了解不同种族群体的PCS对于有效管理至关重要.
研究的目的:
- 描述PCS的发病率,人口统计数据,临床特征,中风位置和大多民族队伍中PCS的结果.
- 为了比较来自中东和北非 (MENA) 地区和其他人口的患者之间的PCS特征.
- 为了确定与PCS患者的不良结果相关的因素.
主要方法:
- 国家中风数据库的回顾性审查 (2014年1月 - 2020年12月).
- 分析每10万成年人口的发病率/年.
- 队列的分层分为MENA和非MENA组进行比较分析.
主要成果:
- PCS发病率从6.3上升到13.2/100,000成年人口/年.
- 队列 (n=1571) 主要是男性 (82.4%),平均年龄为54.9岁.
- 血管风险因素的高患病率 (高血压78.3%,糖尿病61.7%).
- 常见的症状包括虚弱 (58.8%),头 (50.5%) 和言语不清 (36.2%).
- 出院时的依赖或死亡率为39.5%,90天后为27.4%.
- 与非MENA患者相比,MENA患者年轻,血管负担较小,并有更多的近道中风位置.
- 糟糕的结果与年龄的增加,男性性别,MENA国籍和近邻/多地点参与有关.
结论:
- 观察到PCS发病率上升,中东和北非地区的老年男性的发病率显著增加.
- 在中风的位置和中风患者与非中风PCS患者之间的结果存在显著差异.
- 个性化患者护理计划必须考虑到这些种族和地区差异.
- 需要进一步的研究来探索这些观察到的变异的根本原因.
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