了解非酒精性脂肪肝疾病的负担:采取行动的时间
Zobair M Younossi1, Linda Henry1
1Beatty Liver and Obesity Research Program, Inova Health System, Falls Church, VA; The Global NASH Council, Washington, DC, and the Center for Outcomes Research in Liver Diseases, Washington, DC.
非酒精性脂肪肝 (NAFLD) 影响了38%的美国成年人,在30年内增加了50%. 它的患病率在2型糖尿病患者中更高,增加肝病进展和死亡的风险.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 在美国,非酒精性脂肪性肝病 (NAFLD) 的患病率为38%,在过去30年中增加了50%.
- 在2型糖尿病患者中,NAFLD影响了55-70%的人,加剧了健康风险.
- 纳氏体脂肪疾病给患者和经济带来了巨大的负担,但公众和医疗服务提供者的认识很低.
研究的目的:
- 审查NAFLD流行病学.
- 强调NAFLD和2型糖尿病之间的关联.
- 呼吁采取行动,提高NAFLD的认识和管理.
主要方法:
- 对NAFLD患病率和趋势的流行病学综述.
- 对NAFLD与2型糖尿病和死亡率相关性的分析.
- 讨论临床管理策略.
主要成果:
- 纳FLD的患病率显著上升,特别是在2型糖尿病患者中.
- 2型糖尿病增加了NAFLD的进展,肝移植和死亡风险.
- 心血管疾病是NAFLD患者的主要死亡原因,尤其是糖尿病患者.
结论:
- 美国白血病是越来越严重的公共卫生问题,需要紧急关注.
- 有效的风险分层,特殊护理转诊和心脏代谢风险管理至关重要.
- 提高认识和实施系统的管理策略对于应对日益增长的NAFLD负担至关重要.
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