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通过在微晶纤维素和曼尼托尔上的固体分散,增强了glibenclamide的溶解速率,并与酸丁胆相结合

Wanlop Weecharangsan1, Robert J Lee2

  • 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Srinakharinwirot University, Nakhon Nayok, Thailand.

Drug development and industrial pharmacy
|February 22, 2024
PubMed
概括

在微晶纤维素和曼尼托尔上喷雾干燥的glibenclamide固体分散物,含有或不含酸丁胆,显著提高了药物溶解率. 这些配方对口服固体剂型有希望.

关键词:
固体的分散 固体的分散结晶的 结晶的解散率 解散率 解散率这是一种曼尼托尔 (Mannitol).微晶纤维素的微晶纤维素.酸胆是一种酸.表面的表面表面的表面表面的表面

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