脊柱形态的特征根据全球对齐和比例 (GAP) 评分在多样化,无症状的队列:多民族对齐规范性研究
Yong Shen1, Zeeshan M Sardar1, Matan Malka1
1Department of Orthopaedic Surgery, Columbia University Irving Medical Center, The Spine Hospital at New York Presbyterian, New York, NY.
Spine
|February 22, 2024
概括
GAP评分系统适用于各种人群,揭示了许多无症状个体有脊柱 misalignments. 放射性不对齐并不总是意味着病理,强调脊柱对齐的频谱.
科学领域:
- 脊柱研究研究 脊柱研究
- 放射性分析 放射性分析
- 生物机械评估评估
背景情况:
- GAP评分对脊柱形态进行了分类,并预测了成年脊柱形患者的外科手术结果.
- 之前的研究集中在有症状的患者身上;这项研究分析了一个无症状的队列.
- 了解健康人群中的GAP分数分布对于临床解释至关重要.
研究的目的:
- 为了确定GAP分数在多民族调整规范性研究 (MEANS) 队列中的分布.
- 为了在不同的GAP对齐类别,年龄组和国家中比较脊柱形状.
- 评估在无症状的多民族人口中脊柱不对齐的患病率.
主要方法:
- 在五个国家对467名健康志愿者进行了前性,横截面,多中心的研究.
- 使用EOS成像系统测量的斜射线参数.
- 统计分析包括Kruskal-Wallis,Games-Howell和费舍尔的精确测试 (P <0.05).
主要成果:
- 19.5%的无症状志愿者被分类为适度不成比例的,3.6%的严重不成比例的GAP得分.
- 严重不成比例的个体是年长的,并且表现出明显不同的斜参数 (例如,下腰部位,更高的骨盆倾斜).
- 不同国家的受试者之间没有发现GAP分数分布的显著差异.
结论:
- GAP评分系统适用于大型的,多民族的,无症状的队列.
- 脊柱对齐存在于一个频谱上,显著的无症状个体百分比显示中度到严重的不对齐.
- 通过GAP得分识别的放射性失调并不总是表明症状或潜在的病理.
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