全血,血和血小板捐献者的捐赠者并发症率:年龄与经验对比
Yared Paalvast1, Niubel Díaz Padilla1, Sanne Bruijns1
1Donor Medicine, Sanquin Blood Bank, Amsterdam, the Netherlands.
Transfusion
|February 22, 2024
概括
献血者的年龄和经验显著影响献血并发症的发生率. 老年,经验丰富的捐赠者可能有较高的血管昏的风险,需要仔细考虑接受.
科学领域:
- 输血医学 输血医学
- 捐赠者的健康和安全
- 老年医学 老年医学
背景情况:
- 血液银行经常对捐献者施加年龄限制,因为担心并发症率增加.
- 捐赠者的经验是降低并发症率的一个已知的因素,但老年捐赠者往往更有经验,从而产生混效应.
研究的目的:
- 调查捐赠者的年龄与并发症率之间的关系,并考虑捐赠者的经验.
- 为了确定是否与年龄相关的风险在献血仍然存在,当捐赠经验是控制的.
主要方法:
- 从2012-2022年对全血,血和血小板转移捐赠者并发症数据的分析.
- 通过捐赠经验分层的各个年龄组的并发症率的比较 (没有经验的与经验丰富的).
- 后勤回归建模用于量化年龄,经验和其他因素对并发症率的影响.
主要成果:
- 在70-79岁的捐赠者中,中度/严重的血管缩率最高,特别是在血捐赠者中.
- 在70-79岁的年龄组中,失败的静脉穿刺率也很高.
- 血液瘤的发病率呈现出随着年龄的增长而呈现出U形的模式,与年轻群体相比,在老年捐赠者中并不高.
- 疼痛感知随着年龄的增长而下降,尽管70-79岁的患者的疼痛感知率高于65-69岁的患者.
结论:
- 供体并发症概况在充分考虑供体经验时,受到年龄的显著影响.
- 在老年捐赠者中,需要明确沟通中度/重度血管缩的风险增加.
- 在考虑老年人进行初次献血时,建议谨慎行事.
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