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Updated: Jul 2, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

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瘤关联单细胞重新编程CD8+ T细胞成为具有强大的抗瘤作用的中央记忆类细胞

Zeliang Yang1, Liang Liu1, Zhenyu Zhu1

  • 1Department of Pathology, Institute of Systems Biomedicine, School of Basic Medical Sciences, Beijing Key Laboratory of Tumor Systems Biology, Peking University Health Science Center, Beijing, 100191, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 22, 2024
PubMed
概括

瘤相关单细胞 (TAMos) 促进CD8+T细胞的记忆形成,增强抗瘤免疫力. 用L-NMMA抑制氧化合成酶可以提高T细胞的持久性和在癌症免疫治疗中的有效性.

关键词:
CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LG CD300LT细胞耗尽的情况.类似于中央记忆的T细胞.氧化合成酶是一种氧化合成酶.瘤相关单细胞 (TAMos) 是一种与瘤相关的单细胞.

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