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在使用开源自动化胰岛素输送系统的丹麦1型糖尿病儿童和青少年中,流行,安全和代谢控制
Amanda R Fagerberg1,2, Luise Borch1, Kurt Kristensen2
1Department of Pediatrics and Adolescent Medicine, Goedstrup Regional Hospital, Herning, Denmark.
Diabetes technology & therapeutics
|February 22, 2024
概括
开源自动化胰岛素输送系统 (OS-AID) 改善了丹麦1型糖尿病儿童的血糖控制. 这项研究发现,OS-AID使用增加了范围的时间,并降低了HbA1c,没有安全问题.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 糖尿病技术 糖尿病技术
- 代谢性疾病管理管理
背景情况:
- 1型糖尿病 (T1DM) 治疗正在通过集成和传感器技术发展.
- 开源自动化胰岛素输送 (OS-AID) 系统在糖尿病患者中越来越受欢迎.
- 以前的研究表明,OS-AID系统可以增强血糖控制和心理健康.
研究的目的:
- 确定使用OS-AID系统在丹麦患有T1DM的儿童和青少年中的患病率.
- 评估OS-AID系统对代谢控制的影响 (HbA1c,范围内的时间).
- 评估儿童OS-AID用户及其家长对日常生活的安全性和影响.
主要方法:
- 追溯队列研究的设计.
- 通过儿科糖尿病诊所和社交媒体进行招聘.
- 通过调查和对血糖控制指标 (HbA1c,TIR) 的分析收集数据.
主要成果:
- 在2950名丹麦儿科T1DM患者中,OS-AID系统使用率为1.89%.
- 观察到血糖控制的显著改善:时间在范围 (TIR) 从62.29%增加到70.12% (P<0.01).
- HbA1c水平从50.13 mmol/mol下降到47.86 mmol/mol (P<0.05);没有报告任何不良安全事件. 父母报告说,他们的睡眠质量有所改善.
结论:
- 这是第一个报告丹麦儿科OS-AID使用者的研究.
- 在这个人群中,OS-AID系统与改善的血糖控制 (TIR,HbA1c) 有关.
- 在患有T1DM的儿童和青少年中使用OS-AID系统似乎是安全的,对日常生活有益.
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