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Updated: Jul 2, 2025

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通过表面修饰的脂质体纳米载体口服输送万科米辛衍生物FU002

Julia Werner1, Florian Umstätter1, Tobias Hertlein2

  • 1Department of Nuclear Medicine, Heidelberg University Hospital, 69120, Heidelberg, Germany.

Advanced healthcare materials
|February 22, 2024
PubMed
概括

这项研究开发了脂质体纳米载体,用于口服输送抗生素菌素衍生物FU002. 这种配方增强了FU002的成分.

关键词:
细胞透的酸.脂质体是一种脂质体.表面的修改表面的修改四乙烯脂质的四乙烯脂质.范科米辛的结合物是什么具有抗万科胺素耐药性的肠球菌

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The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
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