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针对针对性的JAK/STAT联合抗PD-1/PD-L1疗法的临床前开发和临床研究

Miaomiao Chen1, Siliang Wang1

  • 1Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.

International immunopharmacology
|February 22, 2024
PubMed
概括

瘤通过PD-1/PD-L1相互作用逃避免疫攻击,但耐药性限制了抗PD-1/PD-L1疗法. 针对JAK/STAT途径提供了一种克服这种抗性的策略,并改善癌症治疗结果.

关键词:
药物组合 药物组合是一种药物组合.免疫疗法耐药性 免疫疗法耐药性在JAK/STAT信号通道上.在PD-1/PD-L1中.

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