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Updated: Jul 2, 2025

Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing
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Published on: January 20, 2023

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RNA-LNP传递和蛋白质表达的动力学

Judith A Müller1, Nathalie Schäffler1, Thomas Kellerer2

  • 1Faculty of Physics and Center for NanoScience, Ludwig Maximilians-University, Munich, Germany.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
|February 22, 2024
PubMed
概括

了解脂质纳米粒子 (LNP) 输送的时间对于高效的mRNA基疗法至关重要. 这篇评论详细介绍了LNP动力学,从细胞吸收到蛋白质表达,突出了优化RNA递送的关键因素.

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Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli10:38

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