儿童和青少年结肠膜异位炎的特征:一个多中心研究
Ji-Won Han1, Joonhyuk Son2, Chaeyoun Oh3
1Department of Surgery, Ewha Womans University Seoul Hospital, Seoul, South Korea.
Asian journal of surgery
|February 22, 2024
概括
儿童和青少年的结肠膜炎 (CD) 很少见,但正在增加. 大多数病例都涉及右结肠的单一病变,不如成年人那么严重,往往对保守治疗有反应.
科学领域:
- 胃肠病学 胃肠病学
- 儿科手术 儿科手术
- 放射学 放射学是一门学科.
背景情况:
- 结肠膜炎 (CD) 在全球范围内越来越普遍,但关于儿科和青少年病例的数据仍然有限.
- 这项研究通过调查20岁以下个体的CD特征来解决信息稀缺的问题.
研究的目的:
- 在儿科和青少年群体中表征结肠异炎.
- 分析年轻患者中CD的临床表现,诊断方法,严重程度和治疗结果.
主要方法:
- 一个多中心的,对104名被诊断患有CD的20岁以下患者的回顾性审查.
- 从2003年6月到2020年12月收集的数据来自韩国四家三级医院.
- 通过腹部CT扫描证实了诊断;使用修改后的Hinchey分类来评估严重程度.
主要成果:
- 在17.24 ± 2.4岁 (59.6%男性) 的患者中,CD主要发生在盲目或上升结肠 (99%) 中.
- 大多数病例呈现为单独的病变 (89.4%),并且是轻微的 (改性Hinchey阶段0,Ia或Ib).
- 在大多数病例中,用抗生素进行保守的治疗是有效的 (92.3%),复发率为7.8%.
结论:
- 儿童和青少年的结肠膜炎虽然不常见,但其特点是右侧单独的病变,通常严重程度低于成人.
- 保守的,非手术治疗通常是有效的,突出需要专门的儿科CD指导方针.
- 建议早期诊断和保守的方法,而手术只适用于罕见的复杂病例.
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