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Updated: Jul 2, 2025

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替代Wnt信号轴导致瘤基因诱导衰老的断裂

Viola Kluge1, Melanie Kappelmann-Fenzl1,2, Stefan Fischer2

  • 1Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Cell death & disease
|February 22, 2024
PubMed
概括

研究人员发现了一种新的信号通路,涉及YAP和Wnt分子,允许黑色素瘤细胞绕过基因诱导衰老 (OIS). 这一发现揭示了推动黑色素瘤发展的关键机制,并提供了潜在的治疗点.

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