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Updated: Jul 2, 2025

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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Published on: September 14, 2018

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Cbp1和Cren7形成类似染色体的结构,确保长CRISPR数组的高效转录

Fabian Blombach1, Michal Sýkora2, Jo Case2

  • 1RNAP laboratory, Institute for Structural and Molecular Biology, Division of Biosciences, University College London, Gower Street, London, WC1E 6BT, United Kingdom. f.blombach@ucl.ac.uk.

Nature communications
|February 22, 2024
PubMed
概括

与CRISPR相关的蛋白Cbp1和Cren7形成了调节CRISPR阵列转录的染色体结构. 这种双重机制抑制了不必要的促进子活性,同时增强了硫类细胞中必不可少的CRISPR RNA的产生.

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