生物疗法和口腔粘膜疾病的管理
Claire M Healy1, Sheila Galvin2
1Consultant/Professor in Oral Medicine, Dublin Dental University Hospital, School of Dental Science, Trinity College Dublin, Ireland. claire.healy@dental.tcd.ie.
British dental journal
|February 22, 2024
概括
来自生物体的生物药物正在彻底改变癌症和炎症疾病的治疗方法. 牙医必须了解这些强大的药物,以管理患有全身疾病和口腔粘膜疾病的患者.
科学领域:
- 生物技术和药理学 生物技术和药理学
- 免疫学和瘤学
- 口腔医学是指口腔医学.
背景情况:
- 生物药物是来自生物的先进疗法,主要是单克隆抗体和受体对抗剂.
- 这些药物向特定的细胞因子或细胞,显著影响癌症和免疫介导炎症疾病的管理.
- 一般牙医越来越多地遇到患者使用生物药物治疗各种系统性疾病.
研究的目的:
- 介绍生物制剂的频谱及其系统性指示.
- 详细阐述生物制剂在治疗口腔粘膜疾病中的应用.
- 讨论在牙科中使用生物药物的潜在缺点.
主要方法:
- 对生物药物类别及其作用机制的文献综述.
- 对用生物药物治疗的全身性疾病的分析,重点是对牙科患者相关的情况.
- 审查当前的证据和临床考虑使用生物药物在口腔粘膜疾病.
主要成果:
- 生物学已经改变了诸如头癌和类风湿性关节炎和炎症性肠道疾病等恶性瘤的治疗模式.
- 这些药物在控制免疫介导的口腔粘膜疾病方面发挥着至关重要的作用.
- 了解生物制剂的全身效应和口服影响对于安全的患者护理至关重要.
结论:
- 生物药物代表了现代医学的重大进步,具有广泛的系统应用.
- 牙科专业人员必须了解生物药物,以便有效管理需要牙科护理的患者.
- 需要进一步的研究,以充分阐明生物制剂在口腔医学中的益处和风险.
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