性别不一致和自闭症特征:大脑和行为基础
Behzad S Khorashad1,2, Yanlu Wang3,4, Mats Holmberg5,6
1Department of Women's and Children's Health, Karolinska Institute and University Hospital, 171 77, Stockholm, Sweden.
Archives of sexual behavior
|February 22, 2024
概括
性别失调和自闭症谱系障碍 (ASD) 经常同时发生. 这项研究发现,跨性别个体中更高的自闭症特征与更大的身体不相称性和特定的叶皮层稀释有关,影响社会认知.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 遗传学 遗传学是一种遗传学.
背景情况:
- 性别失调和自闭症谱系障碍 (ASD) 经常同时发生.
- 这种并发症的神经生物学基础及其与性别不一致的关系尚未得到充分理解.
研究的目的:
- 调查性别失调症和ASD的神经生物学相关性.
- 检查自闭症特征,与性别相关的身体不一致性和跨性别和 cisgender 个体的皮质厚度之间的关联.
主要方法:
- 在99名跨性别和99名 cisgender 个体中使用社会响应度量评估了自闭症特征.
- 使用"身体形态"测试测量与性别相关的身体不一致性.
- 研究了与大脑皮层厚度的关联.
主要成果:
- 变性人群表现出明显更高的自闭症特征.
- 更高的自闭症特征与增加的身体不一致性相关.
- 在跨性别个体中,更高的自闭症特征与叶区域的皮质较薄有关,这些区域对社会认知至关重要.
结论:
- 自闭症特征在变性人群中更为普遍,与更大的身体不相称性有关.
- 在跨性别个体中,特定的叶皮层稀疏与自闭症特征有关,主要影响社会认知领域.
- 研究结果表明,性别障碍症和自闭症有明显的神经生物学相关性,这对理解跨性别人口的社会认知有影响.
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