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Updated: Jul 2, 2025

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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菌毒素candidalysin的分泌取决于保存的前体序列

Rita Müller1, Annika König1,2, Sabrina Groth3

  • 1Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute (HKI), Jena, Germany.

Nature microbiology
|February 22, 2024
PubMed
概括

在Candida albicans中的Ece1前体蛋白通过阻断candidalysin自聚,防止自我毒性. 非candidalysin Ece1对于这种真菌毒素的适当折叠和分泌至关重要.

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