吸气性肺炎和其预后因素的离院后预后极差:一项回顾性队列研究
Yuki Honda1,2, Yoichiro Homma3, Mieko Nakamura4
1Department of General Internal Medicine, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Chuo-ku, Hamamatsu, Shizuoka, 430-8558, Japan. y-honda@sis.seirei.or.jp.
患有吸入性肺炎住院的老年患者的长期存活率很差,平均存活时间为369天. 出院时的营养支持,如输管养或肠外营养,显著影响死亡风险.
科学领域:
- 老年病的医生 老年病的医生
- 肺部病理学 肺部病理学
- 临床营养学 临床营养学
背景情况:
- 对于吸入性肺炎患者的长期预后存在有限的证据.
- 吸气性肺炎是老年人的一个重大问题,往往导致住院和复杂的护理需求.
研究的目的:
- 调查出院后的生存时间,并确定因吸气肺炎住院的老年患者的预后因素.
主要方法:
- 对65岁及以上因吸入性肺炎住院的患者进行了回顾性队列研究.
- 分析包括患者人口统计,临床状况,CURB-65分数,营养途径和出院地点.
- 卡普兰-梅尔曲线和考克斯回归模型被用来评估死亡率预测因素.
主要成果:
- 该研究包括209名患者,平均年龄为85岁; 77%在随访期间死亡,平均存活时间为369天.
- 输管养 (aHR=1.70) 和排泄时的肠外营养 (aHR=4.42) 与死亡率的增加密切相关.
- 男性性别和低体重指数 (BMI) 也与较差的结果有关.
结论:
- 患有吸入性肺炎住院的老年患者的长期预后非常差.
- 出院时的营养途径是影响生存的关键预后因素.
- 调查结果突出了针对性干预和进一步研究的必要性,以改善这一弱势群体的结果.
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