了解试验方法研究结果的实施:一种应用实施框架和行为变化模型的混合方法研究.
Taylor Coffey1, Paula R Williamson2, Katie Gillies3
1Health Services Research Unit, University of Aberdeen, Health Services Research Unit, Foresterhill, Aberdeen, AB25 2ZD, UK. taylor.coffey1@abdn.ac.uk.
Trials
|February 23, 2024
概括
实施试验方法研究是具有挑战性的,因为资源有限和缺乏意识. 改善实施的策略包括利用试验网络,为临床试验单位提供包装资源.
科学领域:
- 临床试验 临床试验
- 实施科学 实施科学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 试验方法研究产生了开展临床试验的最佳实践建议.
- 这些建议往往没有被应用到日常实践中.
- 了解实施挑战对于提高试验质量至关重要.
研究的目的:
- 调查在英国临床试验单位实施试验方法研究成果的障碍和促进因素.
- 确定增强采用研究建议的潜在策略.
主要方法:
- 一个混合方法研究,涉及案例研究,调查和半结构面试.
- 从27个英国试验单位采集的调查数据,使用实施研究综合框架.
- 采访了16名高级试验单位成员,使用能力,机会,动机行为模型进行分析.
主要成果:
- 实施率有所不同,对试验进行建议的采用率较高,对报告的采用率较低.
- 主要障碍包括资源限制和缺乏意识.
- 促进者包括参与试验网络和附有资源的建议.
结论:
- 资源限制和意识是实施试验方法研究的重大障碍.
- 利用试验网络和提供量身定制的资源可以加强实施.
- 需要进一步的研究来开发和测试实际实施策略.
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