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Updated: May 2, 2026

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持续和局部化药物库释放使用辐射激活的闪纳米粒子

Mikyung Kang1,2,3, Jeremy Quintana1,2, Huiyu Hu1,4

  • 1Center for Systems Biology, Massachusetts General Hospital Research Institute, 185 Cambridge Street, Suite 5.210, Boston, MA, 02114, USA.

Advanced materials (Deerfield Beach, Fla.)
|February 23, 2024
PubMed
概括

闪纳米粒子 (SciDD) 能够通过X射线辐射疗法 (XRT) 激活精确的癌症药物输送. 这种有针对性的方法提高了癌症治疗的疗效,并通过仅在瘤部位释放细胞毒性有效载荷来减少副作用.

关键词:
旁观者效应是一种旁观者效应.癌症治疗疗法 癌症治疗化学辐射疗法是一种化学辐射疗法.地方区域控制控制.药物前体是药物前体.闪闪发光的纳米粒子

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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
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