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对四种不同的重矿化剂在人体面膜上的重矿化潜力的比较评估:一项体外研究

Giftlin Denny Xavier¹, George Thomas², Sunil Jose²

¹Department of Conservative Dentistry and Endodontics, Sri Venkateshwaraa Dental College, Puducherry, India.

Journal of conservative dentistry and endodontics

|February 23, 2024

概括

与其他药物相比,自我组装 (P11-4) 显示出较高的面膜再矿化. 这种对牙科应用有希望,其性能优于酸酸化 (CPP-ACPF) 和三酸化 (TCP-F) 的酸 (Casein phosphopeptide-amorphous calcium phosphate fluoride).

科学领域:

牙科材料科学牙科材料科学
生物材料工程生物材料工程
皮肤病学皮肤病学皮肤病学

背景情况:

牙损仍然是一个重要的全球健康问题.
重矿化策略对于预防和逆转早期的面膜去矿化至关重要.
评估新型重矿化剂对于推进牙科疗法至关重要.

研究的目的:

为了比较四种商业药物的重矿化潜力:素基酸盐-无形酸化物 (CPP-ACPF),三酸化物 (TCP-F),酸糖 (CSP) 和自组合 (P11-4).
评估这些药物治疗后,去矿物质化的面膜的结构和矿物质变化.

主要方法:

提取的人类牙被准备成样本 (n=44) 带有声音,非矿物质化和重矿物质化区域.
没有矿物质的面膜用CPP-ACPF,TCP-F,CSP或P11-4进行治疗.
用维克斯微硬度 (VMH) 测试来评估重矿化.
使用扫描电子显微镜 (SEM) 和能量分散X射线 (EDX) 分析进行了结构分析和元素组成.

主要成果:

对于群体之间的声音或非矿物质化的面膜,没有观察到VMH的显著差异.
与CPP-ACPF和TCP-F相比,P11-4显示VMH显著更高 (P <0.05).与CPP-ACPF和TCP-F相比,P11-4显示VMH显著更高 (P <0.05).
在 SEM/EDX 分析中,除了 CPP-ACPF 的外,所有剂的矿物质层均,TCP-F 和 P11-4 具有更高的重矿化程度.

结论:

自组合 (P11-4) 在测试剂中表现出最高程度的面膜重矿化.
与CPP-ACPF和TCP-F相比,P11-4在增强面的微硬度和矿物质含量方面表现优越.
这些发现表明P11-4是牙复矿化疗法的一个有前途的药物.

关键词:

素酸是一种酸.在P11-4中,P11-4是指P11-4中,P11-4是指糖酸盐和糖酸盐的使用能量X射线分散分析.这是唾液,唾液.牙重矿化牙的重矿化三酸化物化物的酸.

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