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阿卡塞丁通过阻断MAPK/NF-κB通路和NLRP3炎症酶激活来抑制炎症

Juan Bu1, Yeledan Mahan1, Shengnan Zhang1

  • 1Medical and Translational Research Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.

Frontiers in pharmacology
|February 23, 2024
PubMed
概括

阿卡塞丁抑制NLRP3炎症酶,这是阿尔茨海默氏症等炎症性疾病的关键参与者. 这种天然化合物减少了关键的炎症标志物和信号通路,提供了潜在的治疗益处.

关键词:
通过MAPK路径.通过NF-κB路径.在NLRP3中,NLRP3是NLRP3中的一个.这种药物是阿卡塞丁 (acacetin).一些炎症一些炎症

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