食道外科阿普加尔评分 (eSAS):在接受新辅助疗法和食道切除术的患者中,是术后发病率的预测指标
Qin Wang1, Chi Zhang1, Chen Qi1
1Department of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Thoracic cancer
|February 23, 2024
概括
食道切除手术的阿普加得分 (eSAS) 可以预测食道癌症 (EC) 患者的重大术后发病率. 然而,eSAS与新辅助治疗后的整体存活率或无复发存活率没有相关性.
科学领域:
- 在瘤学瘤学.
- 外科手术的结果
- 医疗信息学 医疗信息学
背景情况:
- 手术Apgar评分 (SAS) 与术后结果有关,但在食道癌 (EC) 中存在局限性.
- 食道癌患者通常在手术前接受新辅助疗法.
- 术后并发症的预测工具在EC中至关重要.
研究的目的:
- 为了评估食道切除术外科阿帕格得分 (eSAS) 对术后发病率的预测值.
- 评估eSAS与EC患者的整体存活率 (OS) 和无复发存活率 (RFS) 之间的关联.
- 为了确定eSAS是否可以预测EC患者在新辅助疗法后的结果.
主要方法:
- 在新辅助疗法后接受手术的221名EC患者的回顾性分析.
- 数据提取包括了手术和瘤相关的因素.
- 主要发病率定义为Clavien-Dindo等级III或更高;Kaplan-Meier分析生存结果.
主要成果:
- eSAS显示了主要手术后发病率的预测值,最佳截止值为6.
- eSAS和糖尿病被确定为主要发病率的独立风险因素.
- 没有发现eSAS和整体存活率 (OS) 或无复发存活率 (RFS) 之间的显著相关性.
结论:
- 在食道癌症患者中,eSAS是主要手术后发病率的潜在预测因素.
- 在这个队列中,eSAS与整体存活率或无复发存活率无关.
- eSAS的临床实用性可能主要用于预测短期并发症,而不是长期存活.
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