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脑卒中和风险:一项丹麦全国范围的基于登记册的研究

Mads Qvist Buur Ebbesen^1,2,3, Julie Werenberg Dreier^2,4, Grethe Andersen^1,3

¹Department of Neurology, Aarhus University Hospital, Denmark (M.Q.B.E., G.A., J.C.).

|February 23, 2024

概括

卒中幸存者面临患的更高风险,特别是在严重卒中后. 这项研究发现风险估计低于之前的研究,因为它考虑了高中风死亡率.

科学领域:

神经学神经学
流行病学流行病学
公共卫生公共卫生

背景情况:

是中风后的一个已知的风险.
关于影响中风后风险的因素存在不确定性,包括年龄,性别,中风类型/严重程度,时间趋势和死亡率.

研究的目的:

为了调查中风后的风险.
分析年龄,性别,中风特征,日历时间和死亡率如何影响中风后风险.

主要方法:

在丹麦 (2004-2018) 进行了前性,全国性,匹配的队列研究.
101,034名中风患者与10:10匹配,与1,010,533名对照人群相匹配.
竞争风险回归和Cox回归模型用于估计发病率和危险比率.

主要成果:

两年间发病率在缺血性中风后为3.0%,脑内出血后为8.6%,对照组为0.7%.
与对照组相比,的危险比率为21.7 (缺血性中风) 和61.3 (脑内出血).
风险随着中风的严重程度而增加,在两年内达到10.5% (非常严重的缺血性中风) 和13.1% (非常严重的脑内出血).

结论:

这项研究提供了与以前的研究相比,对中风后的最新,较低的风险估计.
考虑到高的中风相关死亡率显著影响了风险评估,特别是严重的中风.

关键词:

是一种.发生率的发生率.脑内出血性中风脑内出血性中风缺血性中风中风发作发作这些一次性中风中风中风中风中风

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