歧视,吸烟和心血管疾病风险:对MESA进行温和调解分析
Stephanie H Cook1,2, Erica P Wood1, James H Stein3
1Department of Social and Behavioral Sciences New York University School of Global Public Health New York NY USA.
歧视与西班牙裔女性和男性以及白人男性的动脉疾病风险增加有关,这种风险是由吸烟介导的. 了解这些差异需要采取跨部门的方法来解决心血管疾病的社会决定因素.
科学领域:
- 心血管疾病的研究研究.
- 在健康方面存在差异.
- 健康的社会决定因素
背景情况:
- 动脉内心介质厚度 (cIMT) 和动脉斑块是已知的心血管疾病风险指标.
- 少数群体的人群通常比白人更高的cIMT和斑块患病率.
- 这些基于种族,种族和性别的差异背后的机制仍然不清楚.
研究的目的:
- 调查吸烟在感知歧视和动脉疾病特征之间的关联中扮演的调解角色.
- 检查这些关联在种族,种族和生物性别群体之间有何差异.
主要方法:
- 从动脉样硬化多民族研究 (MESA) 队列的基线数据分析.
- 包括6814名年龄在45-84岁之间的参与者,没有临床心血管疾病.
- 应用性别分层调节调解模型来评估歧视,吸烟和cIMT/斑块之间的关系.
主要成果:
- 歧视与西班牙裔妇女通过吸烟增加状动脉斑块有关.
- 在西班牙裔和白人男性中,因吸烟而导致的歧视与更高的平均cIMT有关.
- 在吸烟中介的西班牙裔男性中观察到对斑块的歧视的积极间接影响.
结论:
- 跨界框架对于理解歧视,社会地位和心血管疾病风险的复杂相互作用至关重要.
- 解决健康的社会决定因素需要承认个体身份和经验的多方面的性质.
- 未来的研究应该纳入交叉性,以阐明心血管疾病风险的差异.
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