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Updated: Jul 2, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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循环胺的DEF环螺旋环核心的合成

Hao Shao1, Wenheng Liu1, Zhengqi Fang1

  • 1Shanghai Key Laboratory of Green Chemistry and Chemical Processes, State Key Laboratory of Petroleum Molecular & Process Engineering, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, 200062, China.

The Journal of organic chemistry
|February 23, 2024
PubMed
概括

实现了循环胺DEF环螺旋环核心的立体选择性合成. 关键步骤包括酶选择性曼尼赫反应和氧化性螺旋化,C-20甲基组配置控制立体化学.

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