双边上腺密码球菌,在免疫能力强的患者中引起上腺功能不充分
Ramneek Kaur1, Naveen Mittal2, Ankita Soni1
1Department of Pathology, Dayanand Medical College & Hospital, Ludhiana, Punjab, India.
Indian journal of pathology & microbiology
|February 23, 2024
概括
菌感染Cryptococcosis,即使在免疫能力强的个体中,也会导致一次性上腺功能不充分. 诊断的帮助是通过细针吸收或活检识别密码球菌生物体.
科学领域:
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
- 医学真菌学 医学真菌学
背景情况:
- 密码球菌病通常影响免疫力低下的患者,通常以脑膜炎或肺部疾病的形式呈现.
- 由于加密球菌感染导致的初级上腺功能不全是罕见的.
- 上腺干扰是一种已知的,尽管不常见的并发症.
研究的目的:
- 报告一种罕见的加密球菌原发性上腺功能缺陷病例,该病例发生在免疫能力较强的患者身上.
- 要突出与这种不常见的呈现相关的诊断挑战和成像发现.
- 强调在类似结核病的临床场景中考虑真菌感染的重要性.
主要方法:
- 一个中年免疫能力强的男性的案例介绍.
- 临床和放射性评估,包括对上腺病变,脏和肺部的成像.
- 通过精细针吸收细胞学和使用特殊染料的活检 (周期性酸-Schiff和Gomori的甲胺银) 确认诊断.
主要成果:
- 这位患者出现了原发性上腺功能不全,双侧上腺病变,壮和千里肺斑点.
- 脑膜炎没有出现.
- 在精细针吸收细胞学和活检上确定了Cryptococcus生物体.
结论:
- 在结核病样临床放射学表现的患者的差异诊断中,应考虑加密球菌病,特别是那些上腺功能不充分的患者.
- 精细针吸入/活检对于确认密码球菌感染和指导治疗至关重要.
- 这一案例强调了加密球菌病在免疫能力强的个体中异常表现的潜力.
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