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患有帕金森病和深度大脑刺激的成年人群中的语言-认知特征:一项比较研究

Alejandro Cano-Villagrasa¹, Miguel López-Zamora², Lorena Romero-Moreno³

¹Faculty of Health Sciences, Valencian International University (VIU), 46002 Valencia, Spain.

European journal of investigation in health, psychology and education

|February 23, 2024

概括

帕金森病 (PD) 患有深度大脑刺激的患者随着疾病的进展,表现出语言和认知能力的下降. 早期PD患者 (I期) 的表现明显好于后期 (II和III期) 的患者.

科学领域:

神经学神经学
神经科学是一个神经科学.
语音和语言病理学语言病理学

背景情况:

帕金森病 (PD) 的特点是运动和非运动障碍,包括语言,沟通和认知方面的缺陷.
深度大脑刺激 (DBS) 手术改善了PD的运动症状,但可能会加剧语言和认知能力的下降.
随着疾病的进展,这种下降变得更加明显,影响患者的自主性和生活质量.

研究的目的:

为了比较经过DBS的帕金森病患者在不同疾病阶段的语言认知表现.
评估疾病进展对患有DBS的PD患者语言和认知功能的影响.

主要方法:

这是一项涉及60名PD患者的准实验性,横截面研究.
根据疾病阶段,参与者被分为三个组:第一阶段 (n=20),第二阶段 (n=20) 和第三阶段 (n=20).
使用MoCA,ACE-III和MetAphas测试来评估语言认知功能,数据通过MANOVA进行分析.

主要成果:

在疾病不同阶段的语言认知表现中观察到统计学上显著的差异 (p < 0.05).
第一阶段的患者表现优于第二阶段和第三阶段的患者.
一个明显的语言和认知能力下降的趋势是显而易见的,随着PD的进展阶段.

结论:

帕金森病的疾病进展在患有DBS的患者中显著损害了语言和认知功能.
观察到的下降会对患者的自主权和整体生活质量产生负面影响.
早期干预和管理策略对于缓解这些非运动性缺陷至关重要.

关键词:

帕金森病是帕金森氏症的一种疾病.认知性的认知性认知深度大脑刺激刺激大脑语言语言语言语言语言语言.

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