在重症监护室的血流感染:不断发展的流行病学和微生物学
Carly Munro1, Marya D Zilberberg2, Andrew F Shorr2
1Medstar Washington Hospital Center, Washington, DC 20010, USA.
Antibiotics (Basel, Switzerland)
|February 23, 2024
概括
在重症监护病房 (ICU) 的血液感染 (BSI) 造成重大伤害. 新出现的数据显示,由SARS-CoV-2等因素推动的发病率增加,以及抗菌素耐药性增加,使患者治疗复杂化.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 微生物学 微生物学
背景情况:
- 在重症监护室 (ICU) 的血液感染 (BSI) 是患者发病率和死亡率的主要原因.
- 在全球范围内,ICU BSIs的微生物学有所不同,不同地区的病原体占主导地位不同.
- 病例发生率急剧增加,特别是在最近的流行病期间,并且与抗菌素耐药性增加有关.
研究的目的:
- 对在重症监护病房中血液感染的新兴文献进行叙事审查.
- 总结目前对ICU BSI流行病学,致病原体和相关挑战的理解.
- 突出最近的流行病和抗菌素耐药性对ICUBSI和患者结局的影响.
主要方法:
- 进行了对新兴文学作品的叙事评论.
- 综合了BSI发生率,致病原体,地理变异和抗菌素耐药性的数据.
- 分析了SARS-CoV-2感染对ICU BSI结果的影响.
主要成果:
- 集中治疗室的BSI与严重的发病率和死亡率有关.
- 全球BSI微生物学不同,在美国,Gram阳性病原体更常见,在其他地区,Gram阴性病原体更常见.
- 由于COVID-19大流行增加了ICU BSI的发病率,而抗菌素耐药性的增加,特别是耐甲基黄金葡萄球菌,耐卡巴尼姆肠杆菌和Acinetobacter baumannii,使治疗复杂化.
结论:
- 对于ICUBSI的预防措施是可用的,对于改善患者的治疗结果至关重要.
- 传染病专家和重症治疗专家之间的合作可以提高ICUBSI的患者护理和结果.
- 解决日益增长的抗菌素耐药性和了解不断变化的BSI流行病学对于ICU的有效管理至关重要.
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