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用不同密封材料的螺杆固定超结构中的细菌菌群:比较临床试验
Kikue Yamaguchi1, Motohiro Munakata1, Kota Ishii1
1Department of Implant Dentistry, Showa University School of Dentistry, 2-1-1 Kita-senzoku, Ota-ku, Tokyo 1458515, Japan.
Bioengineering (Basel, Switzerland)
|February 23, 2024
概括
含的玻璃离子体水泥有效地密封了牙植入物接入孔,显著减少了与周围植入炎相关的细菌负载和物种. 这一发现为预防植入物并发症提供了一个有希望的策略.
科学领域:
- 牙科植入物学 牙科植入物学
- 微生物学 微生物学
- 生物材料科学 生物材料科学
背景情况:
- 在植入物假体中,螺丝固定的超结构是很常见的,因为人们担心围植性炎.
- 周植入炎的特定感染途径,特别是从接入孔的微泄漏,需要进一步的临床研究.
研究的目的:
- 临床研究牙植入物接入孔内的细菌菌群.
- 为了比较不同密封材料的有效性,特别是复合树脂与含的玻璃离子体水泥相比,在控制细菌污染方面.
主要方法:
- 一项临床研究涉及38个部位的19名患有螺丝固定超结构的患者.
- 接入孔用复合树脂 (控制) 或含的玻璃离子体水泥 (测试) 密封.
- 植入后28天收集了细菌样本,并使用DNA杂交方法进行了分析.
主要成果:
- 含的玻璃离子体水泥显著降低了红色,黄色和紫色复合物的14种细菌的数量 (p < 0.05).
- 这种材料还显著降低了来自色,绿色,黄色和紫色复合体的六种物种的细菌比率 (p < 0.05).
- 在测试组中,色,黄色和紫色复合体中的六种细菌物种的植入阳性率明显较低.
结论:
- 含的玻璃离子体水泥证明了作为牙植入物接入孔的密封材料的有效性.
- 这种生物材料显示出减轻细菌入侵和降低围部植入炎风险的潜力.
- 这些发现支持使用含的玻璃离子体水泥来改善牙植入物维护.
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