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乳头甲状腺小癌:偶然和非偶然环境中的病变之间的差异 - - 对这些临床实体和个人经验的考虑

Giorgio Lucandri¹, Giulia Fiori¹, Francesco Falbo¹

¹Department of Surgical Oncology, San Giovanni-Addolorata Hospital, Via Dell'Amba Aradam 9, 00184 Rome, Italy.

Current oncology (Toronto, Ont.)

|February 23, 2024

概括

乳头甲状腺微瘤 (PTMC) 根据发现而有所不同. 在手术后发现的偶发性PTMC (iPTMC) 具有温和的行为,而在手术前诊断的非偶发性PTMC (niPTMC) 可能表现出侵略性特征.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
病理学病理学病理学

背景情况:

乳头甲状腺微瘤 (PTMC) 是一种小型甲状腺癌 (≤10毫米).
它的临床意义受到争论,有两个发现设置:偶然 (iPTMC) 和非偶然 (niPTMC).
iPTMC是在手术后发现的,而niPTMC是在手术前被诊断出来的.

研究的目的:

为了比较偶然和非偶然PTMC的临床和病理特征.
评估iPTMC和niPTMC之间的侵略性和结果的差异.
为PTMC亚型提供量身定制的后续策略.

主要方法:

54个PTMC病例 (28个niPTMC,26个ipTMC) 的回顾性审查.
对患者人口统计,结节特征,病理发现和治疗数据的分析.
结果的比较,包括在平均87个月的随访期间的无病生存率和复发率.

主要成果:

niPTMC病例较年轻,男性/女性比例较低,结节较大,具有更具侵略性的特征 (多焦点,入侵).
niPTMC还显示了更高的TSH,增加了医院的发病率,以及更需要分离.
无病生存率在各组之间没有显著差异,在niPTMC中出现了一次节点复发.

结论:

与iPTMC相比,niPTMC可能呈现出更具侵略性的病理特征.
虽然长期存活率可能相似,但niPTMC需要更紧密的随访,以便早期检测复发.
通过全甲状腺切除术治疗的IPTMC病例可以被认为是治愈的,需要量身定制的激素补充监测.

关键词:

积极监督是指积极的监督.癌症癌症癌症癌症癌症精细的针头针头是非常重要的.这是偶然的偶然事件.微小瘤是什么意思多焦点性是多焦点性的.这是非偶然的,非偶然的.甲状腺是什么?甲状腺是什么?甲状腺切除术是指甲状腺切除术.超声波超声波是指超声波的使用.

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