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罗马尼亚患者慢性乙肝病毒感染的HLA基因的分子分析

Adriana Tălăngescu1,2, Bogdan Calenic1, Dan Florin Mihăilescu3

  • 1Immunology and Transplant Immunology, Carol Davila University of Medicine and Pharmacy, 258 Fundeni Avenue, 022328 Bucharest, Romania.

Current issues in molecular biology
|February 23, 2024
PubMed
概括

在罗马尼亚,某些人类白细胞抗原 (HLA) 基因基因和氨基酸残留提供了对慢性乙型肝炎病毒 (CHB) 感染的保护. 识别这些遗传标记可以改善CHB诊断和管理.

关键词:
氨基酸残留物 氨基酸残留物乙型肝炎病毒 (HBV)人类白细胞抗原 (HLA)下一代测序 (NGS) 是指下一代的测序.

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
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