在中期帕金森病的社会认知和轻度认知障碍
Roberto Fernández-Fernández1,2,3, Guillermo Lahera4,5,6, Beatriz Fernández-Rodríguez1,7
1HM CINAC (Centro Integral de Neurociencias Abarca Campal), Hospital Universitario HM Puerta del Sur, HM Hospitales, 28938 Madrid, Spain.
Behavioral sciences (Basel, Switzerland)
|February 23, 2024
概括
在患有轻度认知障碍 (MCI) 的帕金森病 (PD) 患者中,社会认知 (SC) 受到损害. 情感和认知思维理论 (ToM) 的下降与PD中的MCI有关.
科学领域:
- 神经学 神经学
- 认知神经科学 认知神经科学
背景情况:
- 轻度认知障碍 (MCI) 是帕金森病 (PD) 的一个常见的非运动症状.
- 社会认知 (SC) 涵盖了对社会互动至关重要的能力,包括理解意图和指导行为.
研究的目的:
- 将中期PD患者的SC表现与健康对照 (HC) 进行比较.
- 调查正常认知 (PD-CN) 和MCI (PD-MCI) 的PD患者之间的SC差异.
主要方法:
- 52名PD患者 (被分类为PD-CN或PD-MCI) 和27名HC患者接受了SC评估.
- SC任务包括面部情绪识别 (FER),情感和认知思维理论 (ToM) 和自我监测 (RSMS).
主要成果:
- 在情感和认知ToM任务上,PD-MCI患者的表现比HC更差.
- 与PD-CN和HC组相比,PD-MCI中的认知ToM显著较低.
- 两组之间没有观察到FER或自我监测的显著差异.
结论:
- 在没有认知障碍的非抑郁的中期PD患者中,社会认知仍然完好无损.
- 情感和认知思维理论的下降与帕金森病中的轻度认知障碍有关.
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