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多发性硬化症研究演变:仔细研究深灰质,性功能康复和T调控细胞

Majid Ghareghani1, Serge Rivest1

  • 1Neuroscience Laboratory, CHU de Québec Research Centre, Department of Molecular Medicine, Faculty of Medicine, Laval University, Québec City, QC G1V 4G2, Canada.

Journal of personalized medicine
|February 23, 2024
PubMed
概括

多发性硬化症 (MS) 是一种导致中枢神经系统 (CNS) 损伤的自身免疫性疾病. 研究探讨了它的机制,以找到有效治疗髓和神经元损失的方法.

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T Cell Types and Functions01:24

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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