药剂师驱动的酒精使用障碍查可能会增加长期释放纳尔德的住院使用:单一中心试点研究
Sabrina Snyder1, Niyati Butala1, Andrew M Williams1
1Department of Pharmacy, Arlington Campus, Riverside University Health System, Riverside, CA 92503, USA.
Pharmacy (Basel, Switzerland)
|February 23, 2024
概括
药剂师查增加了在精神病医院住院患者中使用延长释放纳勒 (XR-NTX) 治疗酒精使用障碍 (AUD) 的情况. 这种干预改善了XR-NTX的管理,但没有影响再接收率.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 伴随性物质使用,特别是酒精使用障碍 (AUD),在患有精神疾病的人群中很常见.
- 延长释放纳尔德 (XR-NTX) 是FDA批准的AUD,可以减少酒精的奖励效应.
- 将查整合到精神病学环境中可能会改善AUD治疗的准入.
研究的目的:
- 评估药剂师驱动的选工具是否会增加精神病患者的XR-NTX利用率.
- 评估药剂师查对XR-NTX给药和患者再入院率的影响.
主要方法:
- 药剂师对精神病科的成年住院患者进行了AUD和并发性疾病的查.
- 符合DSM-5 AUD标准和阿片类药物阴性尿液药物查的合格患者是XR-NTX的候选人.
- 关键的终点包括给出的XR-NTX剂量,30天的再入院和建议的接受.
主要成果:
- 药剂师在641名查患者中确定了66名符合条件的患者.
- 与干预前相比,XR-NTX的使用在研究期间从2个增加到8个.
- 在接受XR-NTX和未接受XR-NTX的患者之间,再入院率相似.
结论:
- 一个药剂师驱动的查协议有效地增加了XR-NTX在精神病医院住院患者的AUD给药量.
- 这种方法有望改善AUD药物治疗在患有同时出现精神健康状况的患者中.
- 药剂师的参与可以提高对AUD的基于证据的治疗方法的提供.
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