通过基于MS的蛋白质组学,确定Mortalin作为Mycalin A的主要相互作用物,一种多化C-15乙原蛋白海绵代谢物

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Peptide-based Identification of Functional Motifs and their Binding Partners
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Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: June 30, 2013

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Elva Morretta1, Alessandra Capuano1,2, Gilda D'Urso1

  • 1Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy.

Marine drugs
|February 23, 2024
PubMed
概括

海洋海绵化合物Mycalin A针对Mortalin (GRP75),这是一个涉及癌症的蛋白质. 这种相互作用可能会恢复p53的功能,促进癌细胞的亡.

关键词:
药物亲和度响应性目标稳定性目标稳定性热冲击蛋白质 热冲击蛋白质海洋抗瘤化合物 海洋抗瘤化合物分子对接的分子对接.多重反应监测多重反应的监测.蛋白质组学 蛋白质组学有针对性的有限蛋白质溶解.

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