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调节免疫反应和Cecal微生物群的饮食格力克种子在肉

Deependra Paneru¹, Guillermo Tellez-Isaias², Walter G Bottje²

¹Department of Poultry Science, University of Georgia, Athens, GA 30602, USA.

Veterinary sciences

|February 23, 2024

概括

饮食花种子通过调节免疫基因表达和增强有益的肠道细菌,对肉产生积极影响. 这表明菜种子可以改善家禽的整体健康和肠道微生物群.

科学领域:

动物科学动物科学
免疫学免疫学免疫学
微生物学微生物学

背景情况:

草种子 (FSs) 含有具有潜在免疫调节和改变肠道微生物群的特性的生物活性化合物.
了解肉的这些影响对于改善家禽的健康和表现至关重要.

研究的目的:

为了研究菜种子粉对肉免疫相关基因表达和菌群组成的影响.

主要方法:

144只肉被分为三个组:CON (0克/公斤FS),FS5 (5克/公斤FS) 和FS10 (10克/公斤FS).
在第42天,分别分析了皮质组织和内含量,以检测免疫基因的mRNA表达和微生物群多样性.

主要成果:

草种子降低了关键的炎症和抗菌防御基因 (IL6,IL8L2,CASP6,PTGS2,IRF7,AvBD9,AvBD10,AvBD11) 的调节.
饮食FS改变了状微生物群,增加了Firmicutes,并减少了Actinobacteriota,Gemmatimonadota和Verrucomicrobiota在类层面.
特殊的属,如 *Alistipes*, *Bacteriodes* 和 *Prevotellaceae* 增加了花种子补充剂.

结论:

草种子对肉的免疫特征有有益影响.
补充FS对 brojlers的肠道微生物组合有积极的影响,可能是通过免疫-肠道微生物组相互作用.

关键词:

花草是一种花草.基因表达方式基因表达免疫反应的免疫反应.我们的微生物群.

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