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Piezo1机械感知调节了人类T细胞中对整合素依赖的化学转移

Chinky Shiu Chen Liu1, Tithi Mandal2, Parijat Biswas3

  • 1IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata, India.

eLife
|February 23, 2024
PubMed
概括

Piezo1蛋白对于人类T细胞迁移至关重要,它通过感知机械线索并使整合素招募成为可能. 这种机械感知机制对于T细胞有效地向炎症组织移动至关重要.

关键词:
在F-actin的使用中.一个LFA1一个LFA1这是一个Piezo1.细胞生物学 细胞生物学细胞迁移 细胞迁移化学反应的化学作用.同焦点显微镜的共焦显微镜.焦点粘附激酶的焦点粘附激酶.人类 人类 人类 人类 人类 人类 人类人类T细胞的人类T细胞免疫学 免疫学 免疫学这是一种炎症炎症炎症炎症.干扰反射显微镜干扰反射显微镜机械感知机械感知机器

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