儿童内体积的规范性参考数据:CT体积测量的结果
L A Satanin1, A A Evteev2, S G Rudnev3
1Department of Pediatric Neurosurgery, Burdenko National Medical Research Center for Neurosurgery, Moscow, Russia. lsatanin@nsi.ru.
概括
这项研究为0-17岁的俄罗斯儿童提供了关键的内体积 (ICV) 增长图表,解决了儿科标准中的差距. 这些基于CT扫描的图表有助于临床实践评估大脑和头骨发育.
科学领域:
- 儿科放射学 儿科放射学
- 神经成像是一种神经成像.
- 生物统计学 生物统计学
背景情况:
- 内体积 (ICV) 是评估儿科大脑和头骨发育的一个关键指标.
- 现有的ICV生长标准缺乏来自大型儿科队列的足够数据.
- 临床上需要可靠的儿童ICV参考范围.
研究的目的:
- 为了确定俄罗斯儿童的正常内体积 (ICV) 变化范围.
- 为临床应用制定性别特定的ICV生长标准.
- 验证用于ICV估计的现代自动化系统.
主要方法:
- 分析了673名健康儿童 (0-17岁) 的高分辨率头部CT扫描.
- 内体积 (ICV) 估计使用恩德克斯软件系统.
- 使用GAMLSS和LMS方法的RefCurv软件生成了特定年龄和性别的百分比增长参考.
主要成果:
- 恩德克斯软件衍生的ICV估计显示与传统方法具有很高的可比性.
- 成功构建了特定于性别的儿童内体积 (ICV) 增长图表.
- 基于年龄和性别,为ICV生成了平滑的百分比参考.
结论:
- 这项研究提供了经过验证的ICV生长图表,用于0-17岁儿童的临床使用.
- 该研究使用了673张高分辨率CT图像的强大样本大小.
- 开发的图表支持对儿科大脑和头骨发育的准确评估.
相关概念视频
Imaging Studies for Cardiovascular System V: CT
671
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
671
Imaging Studies III: Computed Tomography
893
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
893
Increased Intracranial Pressure l: Introduction
27
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
27
Increased Intracranial Pressure ll: Pathophysiology
20
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
20


