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Updated: Jul 2, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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发现了基于类固醇的新型基因组胺 H3受体对抗剂/逆对抗剂

István Ledneczki1, Pál Tapolcsányi1, Eszter Gábor1

  • 1Gedeon Richter Plc., 19-21 Gyömrői út, Budapest H-1103, Hungary.

Journal of medicinal chemistry
|February 23, 2024
PubMed
概括

开发了基于类固醇的新型组胺H3受体对抗剂. 有前途的化合物显示出高亲和力,体内对抗性和认知益处,没有hERG或肌肉活性.

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