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在双价mRNA增强后,免疫力和IgG4反应减弱

Ninaad Lasrado1, Ai-Ris Y Collier1, Jessica Miller1

  • 1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Science advances
|February 23, 2024
PubMed
概括

由于免疫印记和IgG4切换,双对应的mRNA增强剂对SARS-CoV-2 XBB变体的耐用性和有效性降低. 未来的疫苗设计需要优化,以获得更广泛的保护.

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