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在宫癌查中进行HPV检测的自取样:范围审查

Tamy Colonetti¹, Maria Laura Rodrigues Uggioni¹, Ana Luiza Meller Dos Santos²

¹Laboratory of Translational Biomedicine, University of Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.

European journal of obstetrics, gynecology, and reproductive biology

|February 23, 2024

概括

人类乳头瘤病毒 (HPV) 检测自取样本是用于宫癌查的可行策略. 这种方法受到患者的青,具有成本效益,并增加了查覆盖率.

科学领域:

妇科妇科医生妇科
在瘤学瘤学.
分子诊断学分子诊断学

背景情况:

子宫癌是全球主要的健康问题,主要是由高风险的人类乳头瘤病毒 (HPV) 类型引起的.
通过查及早检测至关重要,以防止癌前病变的癌症发展.

研究的目的:

系统地审查关于宫癌查中的HPV检测自取样方案的医学文献.
与标准方法相比,评估HPV自取样的患者接受度,成本效益和准确性.

主要方法:

在多个数据库 (MEDLINE,Cochrane Library,VHL,Scopus等) 中进行了全面的文献搜索. 使用关键词:"自我采样"",专业采样"",HPV".
包括的研究被分析为患者接受,成本,和准确性与黄金标准的自我采样.
该审查涵盖了33项研究,包括10项随机临床试验 (46,751名患者) 和23项观察性研究 (142,795名患者).

主要成果:

大多数研究报告了患者对自取样方法的显著偏好.
敏感性分析表明,自取样套件的成本较低通常会提高成本效益.
在自行采集的样本上进行的HPV测试显示了与传统方法相比的准确性.

结论:

使用自收集样本进行HPV检测是用于宫癌查的实用和有效策略.
自取样增加了查覆盖率,是许多女性首选的方法.
这种方法为监测HPV感染和预防子宫癌提供了具有成本效益的解决方案.

关键词:

宫癌宫癌是什么这是一个HPVHPVHPV.人类乳头瘤病毒的人类乳头瘤病毒分子测试分子测试自我采样自动采样.

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