异常的补充运动区域与异常和获得的白发有关
Jinping Xu1, Xiaodong Zhang2, Qinxiu Cheng1
1Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Parkinsonism & related disorders
|February 23, 2024
概括
异常和获得的白发作 (非自愿的眼发作) 在补充运动区域具有共同的脑网络异常. 这一发现突显了补充的机动区域.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 运动障碍 运动障碍
背景情况:
- 斑马,一个焦点 dystonia,涉及非自愿的 orbicularis oculi .
- 固态和获得的形式存在,有不清楚的共享神经支.
研究的目的:
- 为了调查导致获得的白发作的病变是否映射到一个共同的大脑网络.
- 为了比较这个网络的异常在异常发作性白发作患者与对照.
主要方法:
- 使用元分析连接模型绘制损伤联合激活网络映射.
- 对损伤诱导的白发作病例进行系统的文献搜索 (n=21).
- 在异形性白发作患者 (n=42) 与健康对照组 (n=44) 的功能连接性分析.
主要成果:
- 导致白发的异质病变汇聚在一个协同激活的网络中,主要涉及双边补充运动区域.
- 这个网络包括或与大多数白发作相关的病变相邻.
- 异常性白发作患者表现出与左后带带皮层的功能连接性下降.
结论:
- 一种常见的补充运动区域异常存在于异常和获得的白发作中.
- 补充运动区域是一个关键的大脑区域,病理上与白发作有关.
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