基于病理学的脑动脉疾病表型及其放射相关物
Jose Gutierrez1, Daniel Bos2, Tanya N Turan3
1Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, 710 W 168th Street, 6th floor, Suite 639, New York, NY 10032, United States.
概括
协调大脑动脉疾病 (如动脉样硬化) 的术语至关重要. 本综述阐明了病理和成像表型,以改善脑血管疾病的研究和临床实践.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 放射学 放射学是一门学科.
背景情况:
- 脑动脉疾病,包括动脉样硬化,血管炎和剖析,对全球脑血管发病率和死亡率做出了重大贡献.
- 这些疾病与中风风险增加,神经退行和痴呆症有关.
- 精确的术语和脑动脉疾病表型的分类对于推进研究和临床护理至关重要.
研究的目的:
- 审查和标准化大脑大小动脉表型的术语.
- 将病理发现与医学研究和临床实践中使用的成像表型相关联.
主要方法:
- 文献评论专注于脑动脉的病理学研究.
- 对内动脉和小血管疾病的成像表型的分析.
- 基于病理和成像证据的术语协调.
主要成果:
- 动脉样硬化是一个不精确的术语; 特定的病因,如动脉样硬化或纤维形成是首选的.
- 动脉样硬化在病理上是由动脉瘤定义的;其他病理由于治疗含义需要不同的术语.
- 高分辨率成像可以改善内动脉疾病的病理识别.
- 动脉样硬化通常用于小血管疾病,但脂质样硬化不那么准确;需要对小血管壁特征进行客观测量.
结论:
- 对脑动脉疾病表型的标准化术语对于准确的诊断和治疗至关重要.
- 区分不同的动脉病理,特别是动脉样硬化,对于临床管理至关重要.
- 先进的成像技术和客观测量是了解小血管疾病的关键.
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