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SUMO修改了GβL,并调解了mTOR信号传输

Sophia Louise Lucille Park1, Uri Nimrod Ramírez-Jarquín1, Neelam Shahani1

  • 1Department of Neuroscience, The Wertheim UF Scripps Institute, Jupiter, Florida, USA.

The Journal of biological chemistry
|February 23, 2024
PubMed
概括

小型泛素类修饰剂 (SUMO) 附着于G蛋白β子单元类蛋白 (GβL),影响拉巴胺素 (mTOR) 复合体组装和信号的机械性标. 这种SUMOylation对于营养诱导的mTOR通路激活至关重要.

关键词:
在SUMO互动动图案中.在 SUMO 的同位素形式中.这就是SUMO机制.氨基酸刺激的氨基酸刺激激酶信号传递中的激酶信号.lysine-site 调节的规范营养信号的营养信号.后翻译修改后的修改蛋白质蛋白质相互作用

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